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Restriction enzymes, modifying enzymes, buffering solutions, inhibitors, and substrates for use in clinical, research, and general laboratory procedures.
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Gly-Pro-AMC hydrobromide is a fluorescent dye that serves as a specific fluorescent substrate for detecting Dipeptidyl peptidase IV (DPP-IV) activity. It is intended for research use only.
Fluorescent dye
Specific fluorescent substrate for detecting Dipeptidyl peptidase IV (DPP-IV) activity
AMC (CAS No 26093-31-2) is a compound prevalent in biomedical research especially in the study of enzymatic activity Originating from the need to understand biological pathways AMC serves as a substrate in assays measuring enzyme kinetics and activity It is commonly used in studies involving serine proteases and other peptidases due to its ability to release a fluorescent signal upon enzymatic cleavage allowing researchers to monitor real-time enzyme activity Its effectiveness is often observed in nanomolar to low micromolar ranges making it suitable for high-throughput screening applications AMC is frequently applied in cell models and animal studies to evaluate enzyme inhibitors and explore potential therapeutic pathways Experimental concentrations typically depend on the specific research design highlighting its adaptability in various scientific investigations
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AMC Arachidonoyl Amide (AMC-AA) is a fluorogenic fatty acid amide substrate used to measure fatty acid amide hydrolase (FAAH) activity in biochemical assays. It is supplied as a light yellow to yellow solid with high purity for enzymatic studies, and should be stored at -80°C and shipped on dry ice.
Fluorogenic substrate for FAAH activity assays
High purity suitable for biochemical studies
Molecular weight 461.64 and formula C30H39NO3
Light yellow to yellow solid appearance
Recommended storage at -80°C and shipped on dry ice
Available in small quantities for assay development, such as 1 MG
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Ac-DEVD-AMC is a fluorescent substrate of caspase-3/caspase-7. When treated with cell lysate, it releases amino-4-methylcoumarin (AMC) for fluorescence detection, with an excitation wavelength of 380 nm and an emission wavelength of 460 nm.
Purity 99.18%
Molecular weight 675.64
Appearance as a solid
Color white to off-white
Emission wavelength 480 nm
Excitation wavelength 390 nm
Recommended powder storage: -80°C for 2 years, -20°C for 1 year
Recommended storage in solvent: -80°C for 6 months, -20°C for 1 month
In vitro solubility in DMSO: 10 mg/mL (14.80 mM)
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A substrate for enteropeptidase; enteropeptidase recognizes amino acid sequence DDDDK and cleaves after the lysine residue, releasing AFC, which displays ex/em spectra of 400/505 nm
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Recombinant HER2/CD340 protein from rhesus macaque (extracellular residues Q24-T652) is produced in HEK293 cells with a C-terminal His tag and supplied lyophilized for use in antibody characterization, ligand binding assays, and signaling studies.
Mammalian expression preserves native folding and glycosylation.
C-terminal His tag enables affinity purification and detection.
Purity greater than 95% as determined by reducing SDS-PAGE.
Lyophilized from PBS, pH 7.4, for improved stability and storage.
Available in multiple sizes, including a 50 μg vial.
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Arg-Arg-AMC acetate is the acetate salt form of Arg-Arg-AMC. It functions as a fluorescent substrate for cathepsin B and is utilized in cathepsin B activity assays.
Fluorescent substrate for cathepsin B
Used in cathepsin B activity assays
Acetate salt form
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